| Autor: |
Mohammed, Khalil, Abeer, Sharaf Eldin, Ahmed, Sadek, Bahaa M, Badr, Ayman S, Yassin |
| Rok vydání: |
2023 |
| Zdroj: |
The Egyptian journal of immunology. 30(1) |
| ISSN: |
1110-4902 |
| Popis: |
This study evaluated the efficacy of IgE in predicting disease progression in chronic hepatitis B virus (HBV) and HBV related hepatocellular carcinoma (HCC) compared to normal controls. The study included 60 HBV-infected patients. Of these, 30 patients with chronic hepatitis B but not related to HCC and 30 patients with related HCC. Serum level of IgE was measured by ELISA. Serum level of IgE was higher in HCC patients than non-HCC patients (p0.005). Significant correlations were detected between IgE, transaminases (ALT, AST), alpha-fetoprotein and severity scores in chronic hepatitis B (CHB) patients. The level of IgE was correlated with HB viral load. Stronger correlations were evident between IgE, prothrombin time and total bilirubin. In conclusion, IgE levels may be considered as non-invasive markers for monitoring liver disease progression in CHB. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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