Evaluation of predictors of weaning from mechanical ventilation in pediatric patients
Autor: | B L, Baumeister, M, el-Khatib, P G, Smith, J L, Blumer |
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Rok vydání: | 1998 |
Předmět: |
Adult
Male Time Factors Adolescent Patient Selection Age Factors Infant Newborn Infant Reproducibility of Results Sensitivity and Specificity Severity of Illness Index Treatment Outcome Child Preschool Multivariate Analysis Tidal Volume Humans Female Single-Blind Method Child Respiratory Insufficiency Lung Compliance Ventilator Weaning |
Zdroj: | Pediatric pulmonology. 24(5) |
ISSN: | 8755-6863 |
Popis: | Objective criteria for ending mechanical ventilation have not been established for infants and children. A recent study in adult patients developed two new indexes, the Rapid Shallow Breathing Index (RSB) and the CROP Index for predicting success or failure of extubation. We decided to evaluate the applicability of these indices to intubated, mechanically ventilated pediatric patients. For this evaluation the indices were adapted to the physiology of infants and children. A pneumotachograph was used to measure spontaneous tidal volume, respiratory rate and dynamic compliance. The tidal volume and the dynamic compliance were corrected for the patient's body weight. Based on the data collected a cutoff value for each index was determined. Of 47 sets of patient data, 38 (81%) were collected during successful extubations, 9 (19%) during failed extubations. A modified CROP index value ofor = 0.1 ml x mmHg/bpm/kg and a modified RSB index value ofor = 11 bpm/mlkg were identified as predictive of successful extubation. The modified CROP cutoff value produced a sensitivity and specificity of 1.0; respective values for the modified RSB cutoff value are 0.79 and 0.78. Cutoff values ofor = 0.1 andor = 11 for the modified CROP index and RSB index, respectively, appear to be predictive of successful extubation in the pediatric population. Our data identifies the modified CROP index as a superior discriminator between successful and unsuccessful extubation. |
Databáze: | OpenAIRE |
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