[Role of antigen-nonspecific suppressors occurring in stress in the pathogenesis of Langat virus infection in mice]

Autor: S V, Ozherelkov, V V, Khozinskiĭ, B F, Semenov
Rok vydání: 1987
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (11)
ISSN: 0372-9311
Popis: Stress factors of different nature activate antigen-nonspecific suppressors inhibiting different mechanisms of immune response in mice. The adoptive transfer of the population of immunocompetent cells containing stress-induced suppressors to mice infected with Langat virus has been found to lead to the activation of asymptomatic infection. The data obtained in this investigation indicate that the above-mentioned mechanism of the development of antigen-nonspecific immune deficiency is of importance in the pathogenesis of viral infections in man and it explains the onset of diseases (or their aggravation) under the conditions of stress.
Databáze: OpenAIRE