The combined assessment of cellular apoptosis, mitochondrial function and proliferative response to pokeweed mitogen has prognostic value in SIV infection

Autor: A M, del Llano, J P, Amieiro-Puig, E N, Kraiselburd, M J, Kessler, C A, Málaga, J A, Lavergne
Rok vydání: 1993
Předmět:
Zdroj: Journal of medical primatology. 22(2-3)
ISSN: 0047-2565
Popis: Using the assessment of the mitochondrial metabolic activity of freshly isolated blood mononuclear cells, the flow cytometric detection of apoptosis and of the proliferative responses to PWM, SIV-infected macaques were classified in: stage 0, which included all animals with unaffected parameters, and stages 1, 2, and 3, which included animals having one, two, or all three parameters affected, respectively. This novel three-parametric staging system (ISS) provides a new prognostic tool in the longitudinal study of SIV infection.
Databáze: OpenAIRE