Interleukin (IL) -1 β, IL-6 and tumor necrosis factor in patients with seasonal flu
| Autor: | Ramos, José M., García-Navarro, Mar, Moreno, Victoria, González-de-la-Aleja, Pilar, Gimeno-Gascón, Adelina, Merino, Esperanza, Portilla, Joaquín |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Aged
80 and over Male Interleukin-6 Tumor Necrosis Factor-alpha Brief Report gripe Interleukin-1beta virus diseases neumonía Pneumonia Middle Aged Influenza respiratory tract diseases Infección del tracto respiratorio Leukocyte Count C-Reactive Protein Influenza Human Humans Female Respiratory Tract Infections Human Aged |
| Zdroj: | Revista Española de Quimioterapia |
| ISSN: | 1988-9518 0214-3429 |
| Popis: | Introduction The role of tumor necrosis factor (TNF), interleukin (IL)-1β and IL-6 in the pathogenicity of seasonal flu is unknown. Methods We analyzed the profiles of these cytokines in 77 flu patients and 17 controls with non-flu respiratory infection, using molecular biology techniques (real-time polymerase chain reaction). Results Flu patients had lower monocyte counts (p=0.029) and a slightly lower median level of IL-6 (P=0.05) than the control group. Twenty-four flu patients (31.2%) had pneumonia; this group had higher C-reactive proteins (p=0.01) and monocyte levels (p=0.009). Pro-inflammatory cytokines levels did not rise in patients with pneumonia complicating seasonal influenza Conclusion IL-6 levels were lower in adults with influenza. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|