| Autor: |
V, Ormaasen, A, Maeland |
| Rok vydání: |
2002 |
| Předmět: |
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| Zdroj: |
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. 121(29) |
| ISSN: |
0029-2001 |
| Popis: |
HIV-infected persons have a considerably higher risk of developing active tuberculosis than immunocompetent individuals. Tuberculosis is the only opportunistic infection among HIV-infected persons that presents a potential health risk to the general population.We present a review on this topic based on relevant literature and clinical experience.Treatment options are limited because of interactions between rifamycins and protease inhibitors and non-nucleoside analogues. When concomitant therapy against HIV infection and tuberculosis is indicated, we suggest a first-line regimen of rifabutin combined with either indinavir or nelfinavir. For patients without severe immunodeficiency, anti-retroviral therapy can be postponed until the end of the initial phase of the anti-tuberculosis treatment.Treatment of concurrent HIV infection and tuberculosis is complex and may involve multiple drug regimens. Treating the latent infection could in many cases prevent active tuberculosis. All HIV-infected persons should be evaluated with respect to active tuberculosis and latent infection. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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