Popis: |
Morphological study of serial section biopsies from 22 children was made to develop new diagnostic criteria of a latent form of terminal ileitis. The following changes were observed: fibroblastic reaction around the lymphoid follicles, degenerative changes of enterocytes close to the lymphoid follicles; disruption of basal membrane over the lymphoid follicles; penetration of lymphoid cells into the intestinal lumen and their adhesion to the apical membrane of enterocytes; neuroma-like structures as an issue of productive vasculitis. The frequency of the symptoms above 62% does not depend on the sex, age and treatment method. |