Bench-to-bedside review: Microvascular and airspace linkage in ventilator-induced lung injury

Autor:	Marini, John J, Hotchkiss, John R, Broccard, Alain F
Jazyk:	angličtina
Rok vydání:	2003
Předmět:	Capillary Permeability Positive-Pressure Respiration Respiratory Distress Syndrome capillary stress fracture Animals Humans Review ventilator-induced lung injury acute respiratory distress syndrome mechanical ventilation Respiration Artificial Severity of Illness Index vascular injury
Zdroj:	Critical Care
ISSN:	1466-609X 1364-8535
Popis:	Experimental and clinical evidence point strongly toward the potential for microvascular stresses to influence the severity and expression of ventilator associated lung injury. Intense microvascular stresses not only influence edema but predispose to structural failure of the gas-blood barrier, possibly with adverse consequences for the lung and for extrapulmonary organs. Taking measures to lower vascular stress may offer a logical, but as yet unproven, extension of a lung-protective strategy for life support in ARDS.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c53751bb6c738b608a2302b653fe71fd http://europepmc.org/articles/PMC374383 Zobrazit plný text záznamu Full text from SpringerLink