| Autor: |
Panli, Han, Lianxue, Zhang, Yaqi, Fu, Youyu, Fu, Jianxiang, Huang, Jinlin, He, Peihong, Ni, Taimoor, Khan, Yang, Jiao, Zaixing, Yang, Ruhong, Zhou |
| Rok vydání: |
2022 |
| Zdroj: |
Nanoscale. |
| ISSN: |
2040-3372 |
| Popis: |
The selective anti-tumor activity and less toxic nature of hypoxia-activated prodrugs including tirapazamine (TPZ) are harbored by hypoxia levels in tumors, the inadequacy of which leads to failure in clinical trials. Thus, the development of effective clinical applications of TPZ requires advanced strategies to intensify hypoxia levels in tumors effectively and safely. In this study, we designed and fabricated a paclitaxel (PTX)-loaded dual-response delivery system with a low dose ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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