| Autor: |
I I, Parkhomenko, T S, Denisova, B S, Sitnikov, T N, Bogatyrenko, L V, Eliseeva |
| Rok vydání: |
1981 |
| Předmět: |
|
| Zdroj: |
Tsitologiia. 23(8) |
| ISSN: |
0041-3771 |
| Popis: |
Cell transformation by the complete and the incomplete virus SV20 was investigated. To compare the oncogenic properties of human adenoviruses, two types of cell systems--the primary rat embryonic cell culture and the primary rat kidney cell culture--were used. The dependence of DNA concentration on transformation frequency was investigated. With the incomplete virus SV20, the transformation efficiency was more than that with the complete virus (16 and 1-3 percent, resp.). In addition, it has been shown that the primary rat kidney cell culture is more sensitive to transformation than the primary rat embryonic cells culture. The new-born Sirian hamsters being inoculated with virus SV20 DNA, the growth of a tumor being registered in the point of injection 120 days afterwards. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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