The effects of nasal closure on quality of life in patients with hereditary hemorrhagic telangiectasia

Autor: Rhett S, Thomson, Nicole L, Molin, Kevin J, Whitehead, Shaelene, Ashby, Leland, Johnson, P Daniel, Ward, Bryan R, McRae, Kevin F, Wilson, Jamie, McDonald
Rok vydání: 2017
Předmět:
Zdroj: Laryngoscope Investigative Otolaryngology
ISSN: 2378-8038
Popis: Introduction Epistaxis is the most common symptom of hereditary hemorrhagic telangiectasia (HHT). Complete nasal closure is one of the treatment options for patients with severe, intractable epistaxis. In our experience, this surgery can be life changing in a positive sense; but many patients as well as their physicians understandably fear that such a procedure will diminish certain aspects of quality of life (QOL). Methods Case‐control study of HHT patients treated at the University of Utah HHT Center of Excellence with and without nasal closure from January 2005 to January 2016. Patients were matched according to epistaxis severity. Each included patient was issued three surveys: Epistaxis Severity Score (ESS), the Pittsburg Sleep Quality Index (PSQI), and the Nasal Obstruction Symptom Evaluation (NOSE). Results After treatment, the mean PSQI and NOSE scores were not significantly different between the two groups. However, the mean ESS score in the nasal closure group was significantly lower at 1.10 compared to the severe epistaxis group with a mean score of 3.99 (P = .027). Conclusion The results of this study demonstrate that nasal closure significantly improves epistaxis severity without having a significant effect on sleep or nasal obstruction as they relate to QOL. These findings suggest that nasal closure should be considered for HHT patients with chronic severe epistaxis. Level of Evidence 4.
Databáze: OpenAIRE