| Autor: |
Venkataraman, Gopalakrishnan M., Kennedy, Lorna J., Little, Marie-Térèse E., Graves, Scott S., Harkey, Michael A., Torok-Storb, Beverly J., Storb, Rainer |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Popis: |
Major histocompatibility complex genes in mammals include highly polymorphic class I and class II genes that are critical for donor-recipient matching for transplantation. Dogs have served as an effective, directly translatable model for stem/progenitor cell transplantation. Previous analyses of major histocompatibility complex class I genes in dogs point to a single highly polymorphic gene, dog leukocyte antigen (DLA)-88, as an important factor in the success or failure of hematopoietic stem cell transplants. Fifty-nine DLA-88 alleles have been identified and reported so far. Here, we extend this list by presenting 13 novel DLA-88 alleles found in domestic dogs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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