Fuzheng Huayu Formula () prevents rat renal interstitial fibrosis induced by HgCl
| Autor: | Ji-Li, Yuan, Yan-Yan, Tao, Qing-Lan, Wang, Li, Shen, Cheng-Hai, Liu |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Glutathione Peroxidase Superoxide Dismutase Tumor Necrosis Factor-alpha NF-kappa B Down-Regulation Kidney Fibrosis Glutathione Models Biological Rats Sprague-Dawley Oxidative Stress NF-KappaB Inhibitor alpha Malondialdehyde Mercuric Chloride Animals Matrix Metalloproteinase 2 Kidney Diseases Phosphorylation Drugs Chinese Herbal |
| Zdroj: | Chinese journal of integrative medicine. 23(8) |
| ISSN: | 1672-0415 |
| Popis: | To investigate the mechanism of action of Fuzheng Huayu Formula (, FZHY) against renal interstitial fibrosis (RIF) relating to oxidative injury and nuclear factor-kappa B (NF-κB) activity.Thirty-two Sprague-Dawley rats were randomly divided into 3 groups: normal group, model group and FZHY treatment group. The RIF model was induced by oral administration of HgClRenal interstitial fibrosis was induced by HgClFZHY could protect kidney from oxidative injury intoxicated by HgCl |
| Databáze: | OpenAIRE |
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