Correction of oxidative stress in patients with chronic cerebral ischemia

Autor: O A, Goroshko, K N, Novikov, V G, Kukes, V L, Voeikov, E V, Buravleva, A S, Zhestovskaya, N G, Berdnikova, V V, Arkhipov
Rok vydání: 2018
Předmět:
Zdroj: Klinicheskaia meditsina. 94(7)
ISSN: 0023-2149
Popis: A pilot study of the effect of the antioxidant drug ethylmethylhydroxypyridine malate on indicators of oxidative stress in patients with chronic cerebral ischemia. At 6 day course administration investigated the antioxidant in these patients significantly accelerates the process of generation of superoxide anion radical, established by lucigenin-depended chemiluminescence that probably regulate a feedback mechanism oxidase systems. This increases the activity of superoxide dismutase, and reduced the concentration of secondary peroxidation product - malondialdehyde, making reasonable use of antioxidants in the treatment of this pathology.
Databáze: OpenAIRE