| Autor: |
Shyam, Madabhushi, Anjan, Trikha, Rahul K, Anand, Rashmi, Ramachandran, Preet M, Singh, Vimi, Rewari |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine |
| ISSN: |
0972-5229 |
| Popis: |
Background Lactate as a target for resuscitation in patients with septic shock has important limitations. The PcvCO2–PaCO2/CaO2–CcvO2 ratio may be used as an alternative for the same. The primary outcome of the study is to evaluate the correlation between serum lactate and PcvCO2–PaCO2/CaO2–CcvO2 ratio measured at various time points to a maximum of 24 hours in patients with septic shock [mean arterial pressure (MAP) 1.696 at 24 hours of resuscitation predicted 28-day mortality (sensitivity: 80%, specificity 69.2%, area under the receiver operating characteristic curve 0.82). Conclusion The PcvCO2–PaCO2/CaO2–CcvO2 ratio and lactate are positively correlated during the first 24 hours of active resuscitation from sepsis-induced hypotension, and a threshold of 1.696 mm Hg/mL/dL at 24 hours significantly differentiates survivors from nonsurvivors (CTRI/2017/11/010342). How to cite this article Madabhushi S, Trikha A, Anand RK, Ramachandran R, Singh PM, Rewari V. Temporal Evolution of the PcvCO2–PaCO2/CaO2–CcvO2 Ratio vs Serum Lactate during Resuscitation in Septic Shock. Indian J Crit Care Med 2021; 25(12):1370–1376. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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