[Hypercalcaemia and malignant lymphoma. One case report]

Autor:	D, Frein, C, Lavigne, N, Josselin, C, Foussard, N, Sivova, M-P, Moles, G, Berrut
Jazyk:	francouzština
Rok vydání:	2007
Předmět:	Aged 80 and over Male Bone Density Conservation Agents Calcitriol Diphosphonates Testicular Neoplasms Lymphoma Non-Hodgkin Palliative Care Hypercalcemia Humans Pamidronate Prednisone Glucocorticoids
Zdroj:	La Revue de medecine interne. 28(10)
ISSN:	0248-8663
Popis:	Hypercalcaemia occurs in less than 15% of lymphomas but is associated with a poor prognosis. A patient known to have a testicular lymphoma was admitted because of asthenia and weight loss. Hypercalcemia and high serum level of calcitriol were found. A high-grade lymphoma attesting a Richter's syndrome was diagnosed. Palliative treatment consisting in corticosteroids and pamidronate was instituted. Hypercalcaemia in lymphoma has a poor prognosis and is often attributed to an acquired uncontrolled vitamin D 1-alpha-hydroxylase activity by the macrophages close to the lymphomatous cells. Influences of TNFalpha, interleukine 6 and PTHrp are also reported.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c31f2fe58c57feda8ef05a3615e9c185 https://pubmed.ncbi.nlm.nih.gov/17544176 Zobrazit plný text záznamu Full Text from ScienceDirect