| Autor: |
A W, Funkhouser, P J, Katzman, J Z, Sickel, J S, Lambert |
| Rok vydání: |
1998 |
| Předmět: |
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| Zdroj: |
Journal of pediatric hematology/oncology. 20(6) |
| ISSN: |
1077-4114 |
| Popis: |
CD30-positive anaplastic large cell lymphoma (ALCL) has been described in adults with HIV-1 infection but is extremely rare in HIV-1-infected infants and children.A 14-month-old girl with congenitally acquired HIV-1 infection presented with fever and a tender, erythematous, cystic mass on the right labium majorum. The mass was biopsied. Histologic examination and immunohistochemistry were performed.Histologic examination showed Touton-like giant cells resembling histiocytes and focally abundant neutrophils obscuring the lymphoid infiltrate. Immunocytochemistry revealed a CD30-positive ALCL of T-cell lineage.Although non-Hodgkin's lymphoma is known to be associated with HIV-1 infection in children, large cell lymphomas of T-cell lineage are extremely rare in this population. Early diagnosis should be aggressively pursued in an HIV-1-infected child who presents with a fever and cutaneous mass. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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