Metastatic medullary thyroid carcinoma to the breast in a patient with combined medullary and papillary carcinoma of thyroid--a case report

Autor:	Preetha, Alath, Inamdar Naquib Shafi, Ahmed, Aisha, Al-Jassar, Sundus, Hussein, Thasneem, Amir, Salah, Al-Waheeb, Rana, Al-Abdulghani, Sara Shirly, George, Kusum, Kapila
Rok vydání:	2014
Předmět:	Calcitonin Thyroid Cancer Papillary Biopsy Fine-Needle Carcinoma Humans Breast Neoplasms Female Thyroid Neoplasms Thyroglobulin Carcinoma Papillary Aged Carcinoma Neuroendocrine
Zdroj:	Diagnostic cytopathology. 43(4)
ISSN:	1097-0339
Popis:	We report the fine-needle aspiration cytology of a case of medullary thyroid carcinoma (MTC) metastatic to the breast in a 66-year old female within two years of diagnosis of the thyroid tumor. The aspirate of the breast metastases revealed a plasmacytoid population of cells in loose clusters and singly with mild to moderate pleomorphism. Nuclear groves and occasional intranuclear cytoplasmic inclusions were seen. The cells stained positive for calcitonin and negative for thyroglobulin. Use of immunocytochemical methods proved useful to diagnose metastasis which was essential in planning treatment. Cases of metastatic MTC to the breast diagnosed on fine-needle aspirates reported in the literature are reviewed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c2ec79fd331e23a585a01a917abcc283 https://pubmed.ncbi.nlm.nih.gov/25350779 Zobrazit plný text záznamu Plný text