| Autor: |
O A, Gromova, A G, Kalacheva, I Iu, Torshin, T R, Grishina, N V, Iudina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Kardiologiia. 53(10) |
| ISSN: |
0022-9040 |
| Popis: |
Current fundamental research indicates importance of conducting clinical studies of the influence of magnesium content of the body on the potassium homeostasis. In this work we systematically analyze molecular mechanisms through which magnesium regulates potassium homeostasis: ATP-sensitive inward rectifier K-channels, Na+/K(+)-ATPases and their regulatory protein SIK1, transporter SLC12A3 and WNK-kinases. Hyperkalemia as well as hypokalemia require safe and effective prevention and therapy, including restoration of magnesium homeostasis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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