Cardiac synovial sarcoma with translocation (X;18) associated with asbestos exposure

Autor:	C M, Karn, M A, Socinski, J A, Fletcher, J M, Corson, J E, Craighead
Rok vydání:	1994
Předmět:	Adult Chromosome Aberrations Male X Chromosome Asbestos Amphibole Diaphragm Translocation Genetic Heart Neoplasms Sarcoma Synovial Occupational Exposure Humans Pleura Asbestos Amosite Chromosomes Human Pair 18 Lung
Zdroj:	Cancer. 73(1)
ISSN:	0008-543X
Popis:	A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleural plaques indicative of asbestos exposure. These findings raise questions about the possible causation of this tumor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c2a97a0bc7e7f43fb66818b4ebd02c80 https://pubmed.ncbi.nlm.nih.gov/8039130 Zobrazit plný text záznamu Plný text