Economic evaluation of antipsychotic drugs for schizophrenia treatment within the Brazilian Healthcare System

Autor: Leandro Mendonça, Lindner, Antonio Carlos, Marasciulo, Mareni Rocha, Farias, Geder Evandro Motta, Grohs
Rok vydání: 2008
Předmět:
Zdroj: Revista de saude publica. 43
ISSN: 1518-8787
Popis: To assess the cost-utility of first and second-generation antipsychotics for treatment of schizophrenia.A five-year Markov model was constructed based on a survey of the records of patients seen in 2006 at a psychosocial care center in the municipality of Florianopolis, Southern Brazil. Costs were evaluated from the perspective of the Sistema Unico de Saúde (SUS - Unified Healthcare System). Utility was measured in quality-adjusted life years obtained in the literature.The Markov model indicated risperidone and haloperidol utilization before olanzapine as the most cost-effective alternatives.Antipsychotic agents haloperidol and risperidone are more cost-effective than olanzapine. Strategies prioritizing the use of antipsychotics with better cost-effectiveness could optimize resource allocation without necessarily compromising the health of patients treated through the Sistema Unico de Saúde.
Databáze: OpenAIRE