Novel Nanotechnology of TiO

Autor: Daniela Dellosso, Cibim, Miki Taketomi, Saito, Priscila Alves, Giovani, Ana Flávia Sanches, Borges, Vanessa Gallego Arias, Pecorari, Orisson Ponce, Gomes, Paulo Noronha, Lisboa-Filho, Francisco Humberto, Nociti-Junior, Regina Maria, Puppin-Rontani, Kamila Rosamilia, Kantovitz
Rok vydání: 2016
Předmět:
Zdroj: International Journal of Biomaterials
ISSN: 1687-8787
Popis: The aim of this study was to assess the performance of glass ionomer cement (GIC) added with TiO2 nanotubes. TiO2 nanotubes [3%, 5%, and 7% (w/w)] were incorporated into GIC's (Ketac Molar EasyMix™) powder component, whereas unblended powder was used as control. Physical-chemical-biological analysis included energy dispersive spectroscopy (EDS), surface roughness (SR), Knoop hardness (SH), fluoride-releasing analysis, cytotoxicity, cell morphology, and extracellular matrix (ECM) composition. Parametric or nonparametric ANOVA were used for statistical comparisons (α ≤ 0.05). Data analysis revealed that EDS only detected Ti at the 5% and 7% groups and that GIC's physical-chemical properties were significantly improved by the addition of 5% TiO2 as compared to 3% and GIC alone. Furthermore, regardless of TiO2 concentration, no significant effect was found on SR, whereas GIC-containing 7% TiO2 presented decreased SH values. Fluoride release lasted longer for the 5% and 7% TiO2 groups, and cell morphology/spreading and ECM composition were found to be positively affected by TiO2 at 5%. In conclusion, in the current study, nanotechnology incorporated in GIC affected ECM composition and was important for the superior microhardness and fluoride release, suggesting its potential for higher stress-bearing site restorations.
Databáze: OpenAIRE