The relationship between complete hydatidiform mole and serum Vitamin D level: a prospective case-control study

Autor: R, Gündüz, U, Değer, I, Kaplan, N, Bayramoğlu Tepe, S, Yaman Tunç, M S, Içen, E, Ağaçayak, M S, Evsen
Rok vydání: 2022
Předmět:
Zdroj: European review for medical and pharmacological sciences. 26(14)
ISSN: 2284-0729
Popis: This study aimed to determine whether or not there was a relationship between complete hydatidiform mole (CHM) and serum Vitamin D level by comparing CHM patients with two control groups and to determine whether or not Vitamin D deficiency is a risk factor for CHM.This prospective study included 30 patients diagnosed with CHM (case group), 30 patients in the first trimester of a healthy pregnancy (control group), and 30 healthy non-pregnant subjects (control group). A record was made of serum 25-hydroxyvitamin D (25-OH D vitamin) levels, age, body mass index (BMI), gravida, parity, and the number of abortus. The serum 25-OH D vitamin levels were examined in each group and compared between groups.The 25-OH D vitamin level of all the patients in the study was determined as 11.16±8.64 ng/mL. No significant difference was determined between the groups in respect of 25 OH-D vitamin levels. When comparisons were made between the four subgroups according to the 25-OH-D level, no significant difference was determined between the CHM and control groups. When the patients were separated as obese and non-obese groups, no significant difference was determined between the groups.Severe deficiency, deficiency, or insufficient levels of serum Vitamin D are not thought to be risk factors for CHM patients.
Databáze: OpenAIRE