| Autor: |
R L, Rogers, T A, Javed, R E, Ross, G, Virella, R K, Stuart, D, Frei-Lahr |
| Rok vydání: |
1998 |
| Předmět: |
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| Zdroj: |
American journal of hematology. 57(4) |
| ISSN: |
0361-8609 |
| Popis: |
A patient with multiple myeloma was noted to have an IgA deficiency during investigation of a possible transfusion reaction due to IgA deficiency and anti-IgA. Because of the patient's age, otherwise good health, and early stage of disease, he was enrolled in a research treatment protocol that involved an allogeneic bone marrow transplant (BMT). The BMT successfully put the patient in complete remission from his multiple myeloma and corrected his IgA deficiency. Class-specific IgG anti-IgA antibody that had been identified prior to BMT was no longer detectable in his plasma. Anaphylactic transfusion reactions were successfully avoided by using a combination of IgA-deficient and washed blood components including the marrow graft, and IgA-reduced intravenous immunoglobulin. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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