CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers

Autor:	J R, Dinsdale, G K, Griffiths, J, Castelló, J, Maddock, J A, Ortiz, M, Aylward
Rok vydání:	1983
Předmět:	Adult Male Cytidine Diphosphate Choline Time Factors Eye Movements Respiration Blood Pressure Electroencephalography Pupil Choline Electrocardiography Reflex Humans Female Pulse
Zdroj:	Arzneimittel-Forschung. 33(7A)
ISSN:	0004-4172
Popis:	Cytidine diphosphate choline (CDP-choline, citicoline, Somazina) was administered to 12 adult healthy volunteer subjects in two short-term chronic oral dose regimens (600 mg X day-1 and 1g X day-1), each of 5 consecutive days, and compared with a corresponding regimen of matched placebo. Transient headaches were the only untoward events recorded, occurring in 4 and 5 subjects, respectively, on the lower and higher dose regimens but in only one subject during placebo administration.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c18bdba457ebe6d714211fbf4492b6d6 https://pubmed.ncbi.nlm.nih.gov/6684468 Zobrazit plný text záznamu