| Autor: |
M C, Lin, A D, Graham, K A, Polse, N A, McNamara, T G, Tieu |
| Rok vydání: |
2000 |
| Předmět: |
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| Zdroj: |
The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc. 26(3) |
| ISSN: |
0733-8902 |
| Popis: |
Previous studies have shown that 1-hour closed-eye contact lens wear with a low-Dk lens causes a significant reduction in corneal pH and an increase in epithelial permeability. In the present study, we evaluated the effects of super-high-Dk/t soft lenses on corneal epithelial barrier function and stromal pH.Corneal thickness was measured by optical pachometry, while epithelial permeability and stromal pH were measured by fluorophotometry. A paired-eye design was used in which one eye was randomly allocated to wear a high-oxygen-permeable soft lens (CIBAVision Focus/NIGHTDAY (Dk/t= 175) while the other eye did not wear a lens.After 1-hour closed-eye lens wear, neither the difference in corneal swelling (P = 0.206) nor the permeability (P = 0.055) between both eyes was significantly different. The mean pH values under open-eye conditions were 7.66 vs. 7.57 for the treatment and control eyes, respectively (P = 0.082), dropping to 7.27 vs. 7.25 after 1-hour eye closure (P = 0.283).Although our results are limited to a 1-hour observation period, they do provide evidence that high-Dk materials may eliminate corneal acidosis and reduced epithelial barrier function that accompany closed-eye contact lens wear with lower-Dk soft lens materials. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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