Preliminary epidemiological studies on tetracycline resistant plasmids isolated from enteric bacteria in Nigeria

Autor: D K, Olukoya, O A, Daini, M T, Niemogha
Rok vydání: 1993
Předmět:
Zdroj: Tropical and geographical medicine. 45(3)
ISSN: 0041-3232
Popis: In an epidemiological investigation on the genetic determinants responsible for tetracycline resistance in Nigeria, 518 isolates of enteric bacteria from hospitals and clinics were screened for susceptibility to antibiotics. 305 (58.8%) were resistant to tetracycline. The commonest resistance pattern that involved tetracycline resistance was tetr ampr sxtr Smr. Of the 305 isolates, 207 (67.8%) transferred resistant plasmids to Escherichia coli K-12. Altogether, 12 types of plasmids were isolated depending on the phenotypes of antibiotics resistant character borne on the plasmids; they ranged in sizes between 3 to 180 kilobases. The plasmids were evenly distributed in the country. Thus R plasmids are a major reason for resistance to tetracycline encountered in Nigeria.
Databáze: OpenAIRE