Treatment of Raynaud phenomenon in systemic sclerosis

Autor:	P, Sinnathurai, L, Schrieber
Rok vydání:	2012
Předmět:	Scleroderma Systemic Treatment Outcome Phosphodiesterase Inhibitors Animals Disease Management Humans Drug Therapy Combination Raynaud Disease Hydroxymethylglutaryl-CoA Reductase Inhibitors Calcium Channel Blockers
Zdroj:	Internal medicine journal. 43(5)
ISSN:	1445-5994
Popis:	Systemic sclerosis is a connective tissue disease characterised by microvascular injury and excessive fibrosis of the skin and internal organs. Most patients with this condition experience Raynaud phenomenon, usually as the earliest manifestation of disease. In addition to pain and functional impairment, Raynaud phenomenon can produce tissue ischaemia resulting in digital ulceration and gangrene. Current treatments have been only moderately successful in reducing the frequency and severity of Raynaud phenomenon in patients with systemic sclerosis. This review will address treatments available for Raynaud phenomenon in systemic sclerosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c13756c2d50630ecdd739d7b93197d0a https://pubmed.ncbi.nlm.nih.gov/23347192 Zobrazit plný text záznamu Plný text