[The immunogenic activity of the Lassa virus structural proteins]

Autor:	S I, Bystrova, N N, Lemeshko, T V, Shkolina, A S, Vladyko
Rok vydání:	1992
Předmět:	Viral Structural Proteins Immune Sera Viral Core Proteins Antibody Affinity Immunoenzyme Techniques Epitopes Capsid Viral Envelope Proteins Antibody Specificity Animals Immunization Rabbits Lassa virus Glycoproteins
Zdroj:	Voprosy virusologii. 37(1)
ISSN:	0507-4088
Popis:	The immunogenic properties of Lassa virus GP1, GP2, and NP polypeptides were studied in rabbits. Lassa virus NP polypeptide, in contrast to GP1 and GP2 polypeptides, was shown to induce the highest titres of antibodies determined by IFA and ELISA tests. Moreover, the antibody relative avidity experiment showed that the anti-NP antibodies has ELISA index of 0.63 whereas anti-GP1 and anti-GP2 antisera had those of 0.49 and 0.28, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c134671227ff5a2e7c2dd44f8199cb4d https://pubmed.ncbi.nlm.nih.gov/1384241 Zobrazit plný text záznamu