Anorectic and behavioural effects of chronic Cissampelos sympodialis treatment in female and male rats

Autor:	R N, Almeida, M F F, Melo-Diniz, I A, Medeiros, L J, Quintans-Júnior, D S, Navarro, A C G M, Falcão, J C, Duarte, J M, Barbosa-Filho
Rok vydání:	2005
Předmět:	Male Behavior Animal Dose-Response Relationship Drug Plant Extracts Administration Oral Cissampelos Antidepressive Agents Drug Administration Schedule Rats Plant Leaves Eating Animals Female Rats Wistar Phytotherapy
Zdroj:	Phytotherapy research : PTR. 19(2)
ISSN:	0951-418X
Popis:	Male and female rats were treated daily for 13 weeks with an ethanol extract of Cissampelos sympodialis leaves (9, 45 and 225 mg[sol ]kg). The food consumption, body weight and behavioural effects in the open-field test were evaluated by weekly monitoring. The results showed that the extract chronic treatment in female rats (45 and 225 mg[sol ]kg) reduced significantly the food intake and the body weight, and produced several alterations in the open-field test. These findings indicate that repeated oral administration of the extract may produce a sex-dependent difference in anoretic and behavioural effects.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c1229f8877f6f3c09a4c77e480257289 https://pubmed.ncbi.nlm.nih.gov/15852484 Zobrazit plný text záznamu Plný text