Early prediction of nasal continuous positive airway pressure failure in preterm infants less than 30 weeks gestation

Autor:	Anne P, De Jaegere, Johanna H, van der Lee, Caroline, Canté, Anton H, van Kaam
Rok vydání:	2011
Předmět:	Male Respiratory Distress Syndrome Newborn Time Factors Continuous Positive Airway Pressure Infant Newborn Gestational Age Risk Assessment Cohort Studies Logistic Models Risk Factors Multivariate Analysis Humans Female Treatment Failure Infant Premature
Zdroj:	Acta paediatrica (Oslo, Norway : 1992). 101(4)
ISSN:	1651-2227
Popis:	To predict early nasal continuous positive airway pressure failure within the first 2 h after birth in preterm infants.Patient and respiratory support variables significantly associated with continuous positive airway pressure failure in the first 72 h after birth were identified in a cohort of preterm infants30 weeks gestation. Using multivariable logistic regression analysis, risk estimates for early nasal continuous positive airway pressure failure were calculated.From 182 infants included, 62(34%) failed early nasal continuous positive airway pressure. Birth weight ≤800 g, male gender and a fraction of inspired oxygen0.25 at 1 and 2 h of age were significantly associated with early nasal continuous positive airway pressure failure. Combining these variables in a logistic regression model provided a minimal risk estimate for failure of 0.04[0.01-0.23] (female800 g, FiO(2) ≤ 0.25 at 1, and 2 h) and maximal estimate of 0.92[0.44-0.99] (male ≤800 g, FiO(2)0.25 at 1 and 2 h).Combining gender, birth weight and the fraction of inspired oxygen at 1 and 2 h of age allows for a better and more individualized prediction of early nasal continuous positive airway pressure failure in preterm infants less than 30 weeks gestation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c07eae9d304efa3b7513ddc6256f937c https://pubmed.ncbi.nlm.nih.gov/22150698 Zobrazit plný text záznamu Plný text