| Autor: |
A, Cymerman, J T, Maher, J C, Cruz, J T, Reeves, J C, Denniston, R F, Grover |
| Rok vydání: |
1976 |
| Předmět: |
|
| Zdroj: |
Aviation, space, and environmental medicine. 47(10) |
| ISSN: |
0095-6562 |
| Popis: |
The effect of 96 h of exposure to hypobaric hypoxia with and without 3.8% CO2 supplementation was studied in two groups of subjects. Five subjects (CO2) were exposed to 440-465 mm Hg barometric pressure (4000-4400 m), and 4 subjects (no-CO2) were exposed to 455-492 mm Hg (3500-1400 m) in order to produce similar levels of resting end-tidal PO2. After 24 h, 2,3-DPG levels of both groups significantly increased and remained elevated. The CO2 group had higher levels than the non-CO2 group after 48 and 72 h. Concurrent measurements of P50 showed similar changes over the same time course. Mean corpuscular hemoglobin concentrations remained normal for 48 h and then decreased in both groups, the CO2 group showing the larger decrease. We conclude that altitude exposure may produce an increase in 2,3-DPG without the presence of respiratory alkalosis previously thought necessary. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
