| Autor: |
L S, Fall, V, Chams, H, Le Coq, M, Fouchard, J P, M'Bika, A, Gringeri, E, Santagostino, B, Bizzini |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Cellular and molecular biology (Noisy-le-Grand, France). 41(3) |
| ISSN: |
0145-5680 |
| Popis: |
The antiviral effect (AVE) and interferon neutralizing capacity (INC) of sera originating from either seronegative or HIV-infected individuals were determined. As a rule, sera from seropositive subjects exhibited higher AVE titers than sera from seronegative individuals. Similarly, the INC of sera from HIV-infected patients, was most often stronger than that of sera from seronegative individuals. Furthermore, sera from HIV-infected patients actively immunized with i-IFN alpha invariably expressed INC in response to treatment, which was not the case for sera from control unimmunized patients. All sera from HIV-infected patients were found by ELISA to contain antibodies specifically directed to IFN alpha. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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