Ganglioglioma arising from dysplastic cortex

Autor: Xilma R, Ortiz-González, Sriram, Venneti, Jaclyn A, Biegel, Lucy B, Rorke-Adams, Brenda E, Porter
Rok vydání: 2011
Předmět:
Zdroj: Epilepsia. 52(9)
ISSN: 1528-1167
Popis: We report the case of a child who presented at 3 months of age with complex partial seizures, a linear facial nevus, and magnetic resonance imaging (MRI) showing delayed myelination and thickened cortex in the left temporal, parietal, and occipital regions. A repeat 3Tesla MRI scan with and without contrast at 6 months again showed cortical dysplasia of the left hemisphere. No other abnormalities were seen. A third scan at 3 years 6 months showed a 2.5 cm, round, hyperintense lesion on both T(2) and T(1) sequences. The lesion and surrounding dysplastic cortex were resected. Palmini grade IIA dysplasia and a ganglioglioma were diagnosed. These findings suggest that cellular components of cortical dysplasias have oncogenic potential.
Databáze: OpenAIRE