[Changes in the blood serum lipids and lipoproteins of rats in ovariectomy and to the administration of the methyl ester of 6-hydroxy-D-homo-8-isoestrone]

Autor:	I Iu, Kameneva, A G, Shavva, V G, Lozovskiĭ, V E, Ryzhenkov
Rok vydání:	1992
Předmět:	Estrone Lipoproteins Ovariectomy Hypercholesterolemia Ovary Drug Evaluation Preclinical Animals Homosteroids Female Lipids Rats
Zdroj:	Biulleten' eksperimental'noi biologii i meditsiny. 114(8)
ISSN:	0365-9615
Popis:	Ovariectomy of rats resulted in biphasic increase of the blood plasma cholesterol (on days 42-54, 70), the alteration of lipoprotein spectrum. The administration to ovariectomized rats of methyl ether 6-oxy-D-homo-8-isoestrone in a dose of 0.01 mg/kg brought about lowering of serum cholesterol and normalization of lipoproteins spectrum. The above trends were not observed after introduction of 0.01 mg/kg estradiol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::bfda3ba6f9961eefc4ed0892db1ea5aa https://pubmed.ncbi.nlm.nih.gov/1467476 Zobrazit plný text záznamu