Activation of calcium-sensing receptor by allosteric agonists cinacalcet and AC-265347 abolishes the 1,25(OH)

Autor:	Kannikar, Wongdee, Mayuree, Rodrat, Chutiya, Keadsai, Walailak, Jantarajit, Jarinthorn, Teerapornpuntakit, Jirawan, Thongbunchoo, Narattaphol, Charoenphandhu
Rok vydání:	2018
Předmět:	Up-Regulation Fibroblast Growth Factors Rats Sprague-Dawley Fibroblast Growth Factor-23 Calcitriol Intestinal Absorption Pregnancy Animals Humans Lactation Calcium Female Benzothiazoles Cinacalcet Caco-2 Cells Intestinal Mucosa Receptors Calcium-Sensing
Zdroj:	Archives of biochemistry and biophysics. 657
ISSN:	1096-0384
Popis:	Long-term high-calcium intake and intestinal calcium hyperabsorption are hazardous to the body. It is hypothesized that enterocytes possess mechanisms for preventing superfluous calcium absorption, including secretion of negative regulators of calcium absorption and utilization of calcium-sensing receptor (CaSR) to detect luminal calcium. Herein, Caco-2 monolayers were treated with high doses of 1,25(OH)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::bfc814464a12a42f4ce40da453d196d1 https://pubmed.ncbi.nlm.nih.gov/30217510 Zobrazit plný text záznamu Full Text from ScienceDirect