Osteoblast responses to BMP-2-treated titanium in vitro
| Autor: | J L, Ong, H L, Cardenas, R, Cavin, D L, Carnes |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Titanium
Osteoblasts Nitrogen Surface Properties Stem Cells Osteocalcin Bone Morphogenetic Protein 2 Proteins Biocompatible Materials Alkaline Phosphatase Carbon Cell Line Oxygen Mice Phenotype Calcitriol Osteogenesis Transforming Growth Factor beta Protein Biosynthesis Bone Morphogenetic Proteins Materials Testing Animals Electron Probe Microanalysis |
| Zdroj: | The International journal of oralmaxillofacial implants. 12(5) |
| ISSN: | 0882-2786 |
| Popis: | In this study, the phenotypic expression of osteoblast progenitor cells, 2T9, on characterized titanium surfaces was examined in the presence of a bone morphogenetic protein-2 (BMP-2). X-ray photoelectron spectroscopy spectra indicated the presence of titanium dioxide on titanium surfaces, along with surface contaminants such as carbon and nitrogen. In the in vitro study, the activity of BMP-2-treated osteoblast cells on titanium surfaces was marked by significantly higher alkaline phosphatase-specific activity and 1,25 (OH2) vitamin D3-stimulated osteocalcin production when compared to the untreated cells on titanium surfaces. |
| Databáze: | OpenAIRE |
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