Confocal microscopy reveals local SR calcium release in voltage-clamped cardiac cells

Autor:	W G, Wier
Rok vydání:	1995
Předmět:	Electrophysiology Sarcoplasmic Reticulum Ion Transport Microscopy Confocal Animals Calcium Heart Calcium Channels Rats Wistar Rats
Zdroj:	Advances in experimental medicine and biology. 382
ISSN:	0065-2598
Popis:	Confocal microscopy during voltage-clamp depolarization of mammalian heart cells revealed distinct local [Ca2+]i-transients that resulted from Ca2+ released through sarcoplasmic reticulum (SR) release channel(s). When voltage was varied, the latency to occurrence and the relative probability of local [Ca2+]i-transients varied as predicted if SR Ca(2+)-release is linked tightly to Ca2+ flux through co-associated L-type Ca(2+)-channels.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::bf01017099c71f0f44c716e1a5ef1745 https://pubmed.ncbi.nlm.nih.gov/8540416 Zobrazit plný text záznamu