[High-dose chemotherapy with autologous peripheral blood stem cell transfusion in the treatment of advanced testis cancer]

Autor: Y, Akasaka, J, Madarame, S, Yanada, H, Igarashi, A, Kuroda, J, Nakata, Y, Ohishi, N, Kondou, M, Tomita
Rok vydání: 1998
Předmět:
Zdroj: Gan to kagaku ryoho. Cancerchemotherapy. 25(11)
ISSN: 0385-0684
Popis: Four patients with advanced testis cancer were treated by high-dose chemotherapy supporting by autologous peripheral blood stem cell transplantation. High-dose chemotherapy (carboplatin 250 mg/m2 or nedaplatin 200 mg/m2, etoposide 1,500 mg/m2, ifosphamide 7.5 g/m2 was given and peripheral blood stem cell transfusion was performed 72 hours after the last dose of chemotherapy. High-dose chemotherapy. was given followed by 1 or 2 cycles of pre high-dose therapy consisting of cisplatin 100 mg/m2 or carboplatin 500 mg/m2, etoposide 450 mg/m2, ifosphamide 6 g/m2. All 4 patients were evaluable. Three patients obtained a complete response and one showed a partial response. The partial responder was given RPLND. The RPLND specimen showed necrotic tissue.
Databáze: OpenAIRE