| Autor: |
R K, Iagafarova, E I, Potapenko, R I, Shenderova, O A, Iakunova, O L, Korolenok, M O, Kusursuz, E A, Sushkova |
| Rok vydání: |
2003 |
| Předmět: |
|
| Zdroj: |
Problemy tuberkuleza i boleznei legkikh. (10) |
| ISSN: |
1728-2993 |
| Popis: |
Fifty-eight patients with nephrotuberculosis at its peak were found to have a high functional activity of neutrophilic granulocytes, as determined by the lysosomal cation test, by the levels of myeloperoxidase and lactoferrin. The subpopulation of lymphocytes, concentrations of tumor necrosis factor-alpha (TNF-alpha), interleukin-2 (IL-2), as well as those of IL-2 in a combination with its soluble receptor (SR-2) in the serum and supernatant of cellular cultures stimulated by phytohemagglutitin and PPD were studied. The findings suggest that there is a close correlation between the high concentrations of IL-2 and PP-alpha and the decreased content of activated lymphocytes expressing receptors to IL-2 (CD25+). Clinical remission has been ascertained to be attended only by a partial normalization of immunological parameters with antituberculous therapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
