Reversal of visceral hypersensitivity in rat by Menthacarin

Autor: S, Botschuijver, O, Welting, E, Levin, D, Maria-Ferreira, E, Koch, R C, Montijn, J, Seppen, T B M, Hakvoort, F H J, Schuren, W J, de Jonge, R M, van den Wijngaard
Rok vydání: 2017
Předmět:
Zdroj: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 30(6)
ISSN: 1365-2982
Popis: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder associated with altered gastrointestinal microflora and increased nociception to colonic distension. This visceral hypersensitivity can be reversed in our rat maternal separation model by fungicides. MenthacarinIn non-handled and maternally separated rats, we used the visceromotor responses to colorectal distension as measure for visceral sensitivity. We evaluated this response before and 24 hours after water-avoidance stress and after 7 days treatment with MenthacarinMenthacarinThe development of visceral hypersensitivity in maternally separated rats and the Menthacarin
Databáze: OpenAIRE