Cytokines and matrix metalloproteinases mRNA expression in archival human tissues from failed total hip arthroplasty using in situ hybridization and color video image analysis

Autor: Y, Yu, W R, Walsh, D H, Sonnabend, J L, Yang, F, Bonar, B, Markovic, W, Bruce, L, Kohan, M, Neil
Rok vydání: 1998
Předmět:
Zdroj: Bulletin (Hospital for Joint Diseases (New York, N.Y.)). 57(1)
ISSN: 0018-5647
Popis: Reports on the histological and biochemical nature of periprosthetic fibrous/granulomatous tissue has, to date, been largely limited to frozen tissue sections. This study reports the cytokine and matrix metalloproteinase profiles found in periprosthetic interface tissues in THA which have failed due to aseptic loosening and in capsular tissues obtained at primary surgery. The study employs immunohistochemistry, in situ hybridization, and color video image analysis on formalin fixed and paraffin embedded sections.
Databáze: OpenAIRE