Gastric erosions induced by nonsteroidal anti-inflammatory drugs: clinical significance, pathogenesis, and therapeutic perspectives

Autor:	N M, Agrawal, K, Aziz
Rok vydání:	1995
Předmět:	Risk Factors Gastritis Anti-Inflammatory Agents Non-Steroidal Humans Stomach Ulcer
Zdroj:	Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians. 6(3)
ISSN:	1048-9886
Popis:	The development of ulceration and ulcer complications by nonsteroidal anti-inflammatory drugs (NSAIDs) is now well established. Gastric erosions occur in about 60% of patients receiving long-term NSAID therapy. Many clinicians consider such erosions benign in nature and not requiring therapeutic intervention. Recent evidence, however, indicates that gastric erosions predispose rheumatic patients to frank ulcerations and ulcer complications. This brief overview summarizes the clinical dilemma in the diagnosis and treatment of NSAID-induced gastric erosions. Current data suggest that misoprostol has important therapeutic benefits for the treatment and prevention of gastric erosions in patients receiving long-term NSAID therapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::bde2ae8b8f9623f40a8a85795858b08a https://pubmed.ncbi.nlm.nih.gov/7663101 Zobrazit plný text záznamu