Lower skeletal muscle mass on CT body composition analysis is associated with adverse clinical course and outcome in children with COVID-19

Autor: Rida, Salman, Marla B, Sammer, Bettina L, Serrallach, Haleh, Sangi-Haghpeykar, Ananth V, Annapragada, R, Paul Guillerman
Rok vydání: 2021
Předmět:
Zdroj: La Radiologia medica. 127(4)
ISSN: 1826-6983
Popis: To assess the association between body composition measures in children with COVID-19 and severity of the disease course and clinical outcome.A retrospective study of children ( 19 years) with COVID-19 admitted to the hospital who underwent CT of the chest and/or abdomen was conducted. Data compiled from electronic medical records included demographics, body mass index (BMI), length of stay, ICU admission, invasive mechanical ventilation and death. Waist circumference and perimeters for skeletal muscle mass (abdominal, psoas and paraspinal muscles) were measured on an axial CT image at the level of the twelfth thoracic vertebra or first lumbar vertebra using FIJI software.Fifty-seven subjects were identified (54% male, median age 15.6 years, 61% Hispanic, 23% African-American). 25% (14/57) were admitted to the ICU and 21% (12/57) needed intubation. 9% (5/57) died. Waist circumference ranged between 53.2 and 138.4 cm (mean 86.58 ± 18.74 cm) and skeletal muscle mass ranged between 0.6 and 6.8 cmLower skeletal muscle mass is associated with an adverse clinical course and outcome in children with COVID-19.
Databáze: OpenAIRE