[Locoregional chemotherapy of locally advanced breast cancer in a pre-treated patient: case report]

Autor: A, Vagliasindi, L, Valmori, A, Bertagni, A, Campisi, C, Milandri, E, Gianpalma, F, Calzolai, D R, Golfieri, G M, Verdecchia
Rok vydání: 2003
Předmět:
Zdroj: Tumori. 89
ISSN: 0300-8916
Popis: We report of the use of intra-arterial chemotherapy in one case of locally advanced breast cancer, that had been systemically pre-treated. Locoregional chemotherapy was delivered via percutaneous access. The catheter tip was placed into the subclavian artery and into origin of the internal mammary artery; it was removed after every cycle of treatment. The schedule of chemotherapy was: epirubicin 30 mg/m2, mitomycin 7 mg/m2 and 5 fluouracil 1000 mg. Three cycles were administered, and the treatment was well tolerated. The patient responded to intra-arterial chemotherapy, and she subsequently underwent complete surgical resection. Intra-arterial chemotherapy for breast cancer in an uncommon approach to the treatment of locally advanced disease. Nevertheless, in selected cases, it could be a more effective therapeutic option for patients with systemic chemotherapy-resistant disease.
Databáze: OpenAIRE