| Autor: |
D J, Kempf, X C, Wang, S G, Spanton |
| Rok vydání: |
1991 |
| Předmět: |
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| Zdroj: |
International journal of peptide and protein research. 38(3) |
| ISSN: |
0367-8377 |
| Popis: |
A new stereocontrolled synthesis of the psi[CH = CH] dipeptide isostere is described. They key step of the sequence relies on the stereospecific alpha-alkylation of delta-amino-gamma-mesyloxy-alpha,beta-unsaturated esters. The broad availability of nucleophilic alpha-side chains by this method allows the preparation of a wide variety of psi[CH = CH] isosteres with predictable stereochemistry. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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