Role of antiangiogenic VEGF-A

Autor: César, Ríos-Navarro, Luisa, Hueso, Ana, Díaz, Víctor, Marcos-Garcés, Clara, Bonanad, Amparo, Ruiz-Sauri, José M, Vila, María J, Sanz, Francisco J, Chorro, Laura, Piqueras, Vicente, Bodi
Rok vydání: 2019
Předmět:
Zdroj: Revista espanola de cardiologia (English ed.). 74(2)
ISSN: 1885-5857
Popis: Angiogenesis helps to reestablish microcirculation after myocardial infarction (MI). In this study, we aimed to further understand the role of the antiangiogenic isoform vascular endothelial growth factor (VEGF)-ATwo mice MI models were formed: a) permanent coronary ligation (nonreperfused MI); b) transient 45-minute coronary occlusion followed by reperfusion (reperfused MI); in both models, animals underwent echocardiography before euthanasia at day 21 after MI induction. We determined serum and myocardial VEGF-AIn both models, circulating and myocardial VEGF-AIn experimental and clinical studies, higher serum VEGF-A
Databáze: OpenAIRE