der(1)t(1;9): a specific chromosome abnormality in polycythemia vera? Cytogenetic and in situ hybridization studies

Autor: J I, den Nijs van Weert, G C, Beverstock, T, Kievits, H L, Haak, F C, Havik-Bogaard, C H, Leeksma
Rok vydání: 1989
Předmět:
Zdroj: Cancer genetics and cytogenetics. 40(1)
ISSN: 0165-4608
Popis: Two patients with polycythemia vera and an extra der(1)t(1;9) chromosome are reported. In one patient this was found as the sole abnormality. The other patient originally presented with trisomy 9 but later developed an extra der(1) during the further course of the disease with disapperance of the extra chromosome 9. In situ hybridization studies on this latter patient proved that the centromere of chromosome 1 was involved in the formation of the derivative chromosome.
Databáze: OpenAIRE