[Inactivation characteristics of polyene macrolide antibiotics]

Autor: M A, Shneĭder, E V, Komarov, O V, Travkin, E B, Shtil'bans, L A, Rachkovskaia
Rok vydání: 1986
Předmět:
Zdroj: Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology. 31(10)
ISSN: 0233-7525
Popis: Roseofungin, a pentaen was used as an example in investigation of certain characteristics of inactivation of polyenic antibiotics. An inactivation product of the antibiotic having no antiviral or antimycotic activity was isolated by TLC and column chromatography on Sefadex LH-20. UV, IR and EPR spectroscopy showed that this product was cys-tetraen without conjugation of the lactone carbonyl to the polyenic system.
Databáze: OpenAIRE