[The mechanism of the proaggregant action on the thrombocytes of RNA and DNA molecules]

Autor:	R A, Zakharian, L A, Rukhkian
Rok vydání:	1990
Předmět:	Adenosine Diphosphate Blood Platelets Platelet Aggregation Verapamil Humans RNA Calcium RNA Fungal DNA Epoprostenol Stimulation Chemical RNA Double-Stranded
Zdroj:	Nauchnye doklady vysshei shkoly. Biologicheskie nauki. (2)
ISSN:	0470-4606
Popis:	The entrance of extracellular Ca2+ in ADP-stimulated human platelets and phospholipase A2 activity have been studied under the action of Ca precipitates DNA, RNA and dsRNA. The nucleic acids and its Ca complexes (Ca-NA) have been found to induce the aggregation of isolated human platelets by stimulation of extracellular Ca2+ entrance into the platelets and the formation of phosphatidilcholine and phosphatidilethanolamine lysoderivatives having the membranolytic effect.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::bc81d610d6d5bdc79ba35e790366be84 https://pubmed.ncbi.nlm.nih.gov/1693862 Zobrazit plný text záznamu